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Immunogen sequence: MLEVHFVGDDD VLNHILDREG GAKLKKERAQ LLVNPKKIIK KPEYDLEEDD QEVLKDQNYV EIMGRDVQES LKNGSATGGG NKVYSFQNRK HSEKMAK
Highest antigen sequence identity to the following orthologs - mouse 69%, rat 70%.
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: origin recognition complex protein 2 homolog; Origin recognition complex subunit 2; origin recognition complex, subunit 2 homolog
基因别名: ORC2; ORC2L
UniProt ID: (Human) Q13416
Entrez Gene ID: (Human) 4999