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产品信息
H00114882-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
OSBPL8 (NP_001003712.1, 1 a.a. approximately 847 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSQRQGKEAY PTPTKDLHQP SLSPASPHSQ GFERGKEDIS QNKDESSLSM SKSKSESKLY NGSEKDSSTS SKLTKKESLK VQKKNYREEK KRATKELLST ITDPSVIVMA DWLKIRGTLK SWTKLWCVLK PGVLLIYKTQ KNGQWVGTVL LNACEIIERP SKKDGFCFKL FHPLEQSIWA VKGPKGEAVG SITQPLPSSY LIIRATSESD GRCWMDALEL ALKCSSLLKR TMIREGKEHD LSVSSDSTHV TFYGLLRANN LHSGDNFQLN DSEIERQHFK DQDMYSDKSD KENDQEHDES DNEVMGKSEE SDTDTSERQD DSYIEPEPVE PLKETTYTEQ SHEELGEAGE ASQTETVSEE NKSLIWTLLK QVRPGMDLSK VVLPTFILEP RSFLDKLSDY YYHADFLSEA ALEENPYFRL KKVVKWYLSG FYKKPKGLKK PYNPILGETF RCLWIHPRTN SKTFYIAEQV SHHPPISAFY VSNRKDGFCL SGSILAKSKF YGNSLSAILE GEARLTFLNR GEDYVMTMPY AHCKGILYGT MTLELGGTVN ITCQKTGYSA ILEFKLKPFL GSSDCVNQIS GKLKLGKEVL ATLEGHWDSE VFITDKKTDN SEVFWNPTPD IKQWRLIRHT VKFEEQGDFE SEKLWQRVTR AINAKDQTEA TQEKYVLEEA QRQAARDRKT KNEEWSCKLF ELDPLTGEWH YKFADTRPWD PLNDMIQFEK DGVIQTKVKH RTPMVSVPKM KHKPTRQQKK VAKGYSSPEP DIQDSSGSEA QSVKPSTRRK KGIELGDIQS SIESIKQTQE EIKRNIMALR NHLVSSTPAT DYFLQQKDYF IIFLLILLQV IINFMFK
靶标信息
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ORP-8; OSBP-related protein 8; Oxysterol-binding protein-related protein 8
基因别名: KIAA1451; MST120; MSTP120; ORP8; OSBP10; OSBPL8
UniProt ID: (Human) Q9BZF1
Entrez Gene ID: (Human) 114882
negative regulation of sequestering of triglyceride
phospholipid transport
negative regulation of cell migration
activation of protein kinase B activity
fat cell differentiation
positive regulation of insulin receptor signaling pathway
positive regulation of protein kinase B signaling
protein localization to nuclear pore
positive regulation of glucose import in response to insulin stimulus
