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OSGEP Antibody (MA5-25567) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a OSGEP monoclonal antibody (Product # MA5-25567).
产品信息
MA5-25567
产品规格
种属反应
Dog,
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI9E3
抗原
Human recombinant protein fragment corresponding to amino acids 1-335 of OSGEP produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723437
靶标信息
Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hOSGEP; mOsgep; N6-L-threonylcarbamoyladenine synthase; O-sialoglycoprotease; O-sialoglycoprotein endopeptidase; O-sialoglycoprotein endopeptidase {ECO:0000255|HAMAP-Rule:MF_03180}; OSGEP; pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1; probable O-sialoglycoprotein endopeptidase; probable tRNA N6-adenosine threonylcarbamoyltransferase; probable tRNA N6-adenosine threonylcarbamoyltransferase {ECO:0000255|HAMAP-Rule:MF_03180}; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; Prsmg1/Gcpl1; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255|HAMAP-Rule:MF_03180}; tRNA N6-adenosine threonylcarbamoyltransferase; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255|HAMAP-Rule:MF_03180}
基因别名: 1500019L24Rik; GCPL-1; GCPL1; KAE1; OSGEP; OSGEP1; PRSMG1
UniProt ID: (Human) Q9NPF4, (Rat) Q9WVS2, (Mouse) Q8BWU5
Entrez Gene ID: (Human) 55644, (Dog) 100687555, (Rat) 290028, (Mouse) 66246
metal ion binding
N(6)-L-threonylcarbamoyladenine synthase
transferase activity, transferring acyl groups other than amino-acyl groups
dihydrolipoamide branched chain acyltransferase activity
sterol O-acyltransferase activity
N-acetyltransferase activity
O-acyltransferase activity
palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity
carnitine O-acyltransferase activity
acetyltransferase activity
C-acyltransferase activity
palmitoyltransferase activity
N-acyltransferase activity
acylglycerol O-acyltransferase activity
serine O-acyltransferase activity
O-acetyltransferase activity
O-octanoyltransferase activity
octanoyltransferase activity
O-palmitoyltransferase activity
S-acyltransferase activity
S-acetyltransferase activity
S-malonyltransferase activity
malonyltransferase activity
C-palmitoyltransferase activity
transferase activity
transferase activity, transferring acyl groups
succinyltransferase activity
N-succinyltransferase activity
O-succinyltransferase activity
S-succinyltransferase activity
sinapoyltransferase activity
O-sinapoyltransferase activity
peptidyl-lysine N6-myristoyltransferase activity
peptidyl-lysine N6-palmitoyltransferase activity
benzoyl acetate-CoA thiolase activity
3-hydroxybutyryl-CoA thiolase activity
3-ketopimelyl-CoA thiolase activity
N-palmitoyltransferase activity
myristoyltransferase activity
acyl-CoA N-acyltransferase activity
protein-cysteine S-myristoyltransferase activity
protein-cysteine S-acyltransferase activity
dihydrolipoamide S-acyltransferase activity
glucosaminyl-phosphotidylinositol O-acyltransferase activity
ergosterol O-acyltransferase activity
lanosterol O-acyltransferase activity
naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity
2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity
2-methylhexanoyl-CoA C-acetyltransferase activity
butyryl-CoA 2-C-propionyltransferase activity
2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity
L-2-aminoadipate N-acetyltransferase activity
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity
keto acid formate lyase activity
Ras palmitoyltransferase activity
azetidine-2-carboxylic acid acetyltransferase activity
peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
acetyl-CoA:L-lysine N6-acetyltransferase
RNA processing factor
