Invitrogen

OTC Polyclonal Antibody

OTC Antibody in Immunohistochemistry (IHC)

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OTC Antibody (PA5-51416) in IHC

Immunohistochemical staining of OTC in human cerebral cortex, duodenum, liver and testis using OTC Polyclonal Antibody (Product # PA5-51416) (A) shows similar protein distribution across tissues to an independent OTC Polyclonal Antibody (B).

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OTC Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of OTC demonstrates antibody specificity. Immunohistochemical analysis of OTC using anti-OTC Polyclonal Antibody (Product # PA5-51416), shows significant staining of OTC in human liver and shows minimal or weak staining in human kidney tissues. The relative expression levels of OTC within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-51416

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:50

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human OTC. Recombinant protein control fragment (Product #RP-91883).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2645102

产品详细信息

Immunogen sequence: QLKGRDLLTL KNFTGEEIKY MLWLSADLKF RIKQKGEYLP LLQGKSLGMI FEKRSTRTRL STETGFALLG GHPCFLTTQD IHLGVNESLT DTARVLSSMA DAVLAR

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

靶标信息

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

仅用于科研。不用于诊断过程。未经明确授权不得转售。