Invitrogen

OTUD6A Polyclonal Antibody

OTUD6A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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OTUD6A Antibody (PA5-62772) in IHC (P)

Immunohistochemical analysis of OTUD6A in human skeletal muscle using OTUD6A Polyclonal Antibody (Product # PA5-62772) shows no positivity in myocytes as expected.

OTUD6A Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-62772

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

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免疫组化（石蜡） (IHC (P))

1:1,000-1:2,500

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human OTUD6A. Recombinant protein control fragment (Product #RP-99994).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2645119

产品详细信息

Immunogen sequence: HRQELEKFQD DSSIESVVED LAKMNLENRP PRSSKAHRKR ERMESEERER QESIFQAEMS EHLAGFKREE E

Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 51%.

靶标信息

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA2 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and AR.

Communications biology

Fu X,Zhao J,Yu G,Zhang X,Sun J,Li L,Yin J,Niu Y,Ren S,Zhu Y,Xu B,Huang L

PA5-62772 was used in Western Blot to explore the pathological role of ovarian tumor (OTU) subfamily deubiquitinase in prostate cancer.

Tue Mar 01 00:00:00 UTC 2022

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and AR.

Communications biology

Fu X,Zhao J,Yu G,Zhang X,Sun J,Li L,Yin J,Niu Y,Ren S,Zhu Y,Xu B,Huang L

PA5-62772 was used in Western Blot to explore the pathological role of ovarian tumor (OTU) subfamily deubiquitinase in prostate cancer.

Tue Mar 01 00:00:00 UTC 2022

Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc.

Cell death and differentiation

Peng Y,Liu J,Wang Z,Cui C,Zhang T,Zhang S,Gao P,Hou Z,Liu H,Guo J,Zhang J,Wen Y,Wei W,Zhang L,Liu J,Long J

PA5-62772 was used in Western Blot to indicate that OTUD6A is a physiological DUB for c-Myc in PrCa setting and specifically promotes prostatic tumorigenesis through stabilizing c-Myc oncoprotein.