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产品信息
PA5-31665
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 87 and 274 of Mouse mOvo2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2549138
产品详细信息
Recommended positive controls: HCT-116, HCT-116 nuclear extract, mouse testis.
Predicted reactivity: Human (92%), Mouse (100%), Rat (98%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription regulator.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hOvo2; MOVO-B zinc finger protein; MOVO-C zinc finger protein; mOvo2; OVO homolog-like 2; Transcription factor Ovo-like 2; Zinc finger OVO2; Zinc finger protein 339; Zinc finger protein mOVO
基因别名: 1700108N11Rik; 1810007D21Rik; EUROIMAGE566589; M-OVO; M-OVO-A; M-OVO-B; MOVO; movo2; Ovo2; OVOL2; PPCD1; Zfp339; ZNF339
UniProt ID: (Human) Q9BRP0, (Mouse) Q8CIV7
Entrez Gene ID: (Human) 58495, (Mouse) 107586
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
metal ion binding
nucleic acid binding
transcription factor activity, sequence-specific DNA binding
transcription regulatory region DNA binding
angiogenesis
neural crest cell migration
neural fold formation
heart looping
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
heart development
negative regulation of cell proliferation
epidermis development
epidermal cell differentiation
dorsal/ventral pattern formation
negative regulation of epithelial to mesenchymal transition
regulation of keratinocyte proliferation
negative regulation of transcription by competitive promoter binding
negative regulation of keratinocyte differentiation
positive regulation of keratinocyte differentiation
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
regulation of cell cycle
endocardium formation
heart trabecula formation
labyrinthine layer blood vessel development
negative regulation of stem cell proliferation
