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产品信息
PA5-22177
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 281 of OXSR1 (Uniprot ID#O95747)
偶联物
形式
Liquid
浓度
0.58 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152987
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (99%), Rat (98%), Xenopus laevis (95%), Pig (99%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
OXSR1 serine/threonine kinase or (OSR1) is activated by osmotic stresses and regulates downstream protein kinases such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during the DNA damage process. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C6orf182; CEP57R; OTTHUMP00000209062; Oxidative stress-responsive 1 protein; oxidative-stress responsive 1; OXSR1; Serine/threonine-protein kinase OSR1
基因别名: KIAA1101; OSR1; OXSR1
UniProt ID: (Human) O95747
Entrez Gene ID: (Human) 9943
protein phosphorylation
response to oxidative stress
peptidyl-threonine phosphorylation
signal transduction by protein phosphorylation
intracellular signal transduction
cellular hypotonic response
negative regulation of potassium ion transmembrane transporter activity
negative regulation of rubidium ion transmembrane transporter activity
