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Oct-2 Antibody (39-5400) in WB
Western blot analysis was performed on nuclear enriched extracts (30 µg lysate) of Raji (Lane 1), Ramos (Lane 2), NTERA-2 (Lane 3), MOLT4 (Lane 4), NCCIT (Lane 5), A549 (Lane 6), HeLa (Lane 7), HEK-293 (Lane 8) and Jurkat (Lane 9). The blot was probed with Anti- Oct-2 Mouse Monoclonal Antibody (Product # 39-5400, 1 µg/mL) and detected by chemiluminescence using Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (Product # A28177, 0.25 µg/mL, 1:4000 dilution). A 62 kDa band corresponding to Oct-2 was observed in Raji, ... View More
产品信息
39-5400
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
ZO001
抗原
Synthetic peptide derived from the C-terminus of human Oct2.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.1% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2533419
靶标信息
OCT-2 is a transcription factor belonging to the POU homeo-domain family that binds to the Ig gene octamer sites regulating B cell specific genes. OCT-2 protein expression is not restricted to B cells, although expression levels are much higher in these cells. OCT-2 expression is reported to be significantly greater in germinal center derived lymphomas, although other B cell lymphomas also display high levels of expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: homeobox protein; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain, class 2, transcription factor 2
基因别名: Oct-2; OCT2; OTF2; POU2F2
UniProt ID: (Human) P09086
Entrez Gene ID: (Human) 5452
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein domain specific binding
sequence-specific DNA binding
