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产品信息
PA5-32956
产品规格
种属反应
Human,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from internal region of human OPN3 / Encephalopsin.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550417
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Dog, Panda, Rabbit (94%); Horse, Opossum (88%); Turkey (81%).
For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. May play a role in encephalic photoreception. Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Encephalopsin; NMO-1; opsin 3 (encephalopsin, panopsin); Opsin-3; Panopsin; protein phosphatase 1, regulatory subunit 116
基因别名: ECPN; OPN3; PPP1R116
UniProt ID: (Human) Q9H1Y3
Entrez Gene ID: (Human) 23596, (Rat) 498289
