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Invitrogen
Orexin Receptor 1 Polyclonal Antibody
FIGURE: 1 / 5
Orexin Receptor 1 Antibody (PA5-33837) in IHC (P)
Immunohistochemistry analysis of Orexin Receptor 1 in rat brain, Purkinje neurons. Samples were incubated with Orexin Receptor 1 polyclonal antibody (Product # PA5-33837). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-33837
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Pig,
Rabbit,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 14 amino acid peptide from 2nd extracellular domain of human HCRTR1 / Orexin Receptor 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551206
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bovine, Rabbit, Pig, Platypus (100%).
Target Information
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein-coupled receptor; Hcrt receptor 1; hypocretin (orexin) receptor 1; hypocretin receptor 1; Hypocretin receptor type 1; hypocretin receptor-1; Orexin a receptor; orexin receptor 1; Orexin receptor type 1; orexin receptor-1; Orexin-1 receptor; Orexin/Hypocretin receptor type 1; Ox-1-R; OX-R1; OX1 receptor; ox1-R; ox1R; type 1 orexin receptor; G protein-coupled hormone receptor; type 1 orexin receptor; G protein-coupled receptor
Gene Aliases: HCRTR1; Hctr1; OX1R
UniProt ID: (Bovine) Q0GBZ5, (Pig) O97661, (Human) O43613, (Rat) P56718
Entrez Gene ID: (Bovine) 282248, (Pig) 387287, (Human) 3061, (Rabbit) 100352294, (Rat) 25593
neuropeptide signaling pathway
feeding behavior
regulation of cytosolic calcium ion concentration
positive regulation of ERK1 and ERK2 cascade
chemical synaptic transmission
cellular response to hormone stimulus
regulation of circadian sleep/wake cycle, sleep
response to peptide
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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