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P2X3 Receptor (extracellular) Polyclonal Antibody

P2X3 Receptor (extracellular) Antibody in Immunocytochemistry (ICC/IF)

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P2X3 Receptor (extracellular) Antibody (APR-026-200UL) in ICC/IF

Expression of P2RX3 in rat PC12 cells - Cell surface detection of P2RX3 in intact living rat pheochromocytoma (PC12) cells. A. Extracellular staining with Anti-P2X3 Receptor (extracellular) Antibody (#APR-026), (1:50, red) followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody . B. DAPI was used as the counter stain (blue). C. Merge images of A and B.

P2X3 Receptor (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))

P2X3 Receptor (extracellular) Antibody in Western Blot (WB)

P2X3 Receptor (extracellular) Antibody in Flow Cytometry (Flow)

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产品信息

APR-026-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化（冰冻） (IHC (F))

Assay-dependent

免疫细胞化学 (ICC/IF)

1:50

流式细胞分析 (Flow)

2.5 µg

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)KGFGRYANRVMDVSD, corresponding to amino acid residues 65-79 of rat P2X3 receptor, Extracellular

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

仅用于科研。不用于诊断过程。未经明确授权不得转售。