Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-79778
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human P2X5 recombinant protein (Position: D333-T422).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746893
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue. IHC: Mouse Brain Tissue, Rat Brain Tissue.
Target Information
Mmgt2 mediates Mg(2+) transport and may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells. Magnesium is an essential metal, but few selective transporters have been identified. The two separate gene products, Mmgt1 and Mmgt2, comprise the family that we have termed membrane Mg(2+) transporters (MMgTs), and the proteins reside in the membrane and mediate Mg(2+) transport. The transport of Mg(2+) is saturable and studies have identified that Mmgt2 fusion proteins reside in the Golgi complex and post-Golgi vesicles, including the early endosomes in COS-7 cells transfected with the respective tagged constructs. Among related pathways for Mmgt2 are transport and binding events, in particular, transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; Membrane magnesium transporter 2; membrane magnesium transporter 2 {ECO:0000250|UniProtKB:Q8R3L0}; MGC47755; mmgt2; mmgt2 {ECO:0000250|UniProtKB:Q8R3L0}; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 5; purinergic receptor P2X, ligand-gated ion channel, 5; purinergic receptor P2X5-2
Gene Aliases: AI852046; LRH-1; Mmgt2; P2RX5; P2X5; P2X5FL; P2X5R; RGD1311260
UniProt ID: (Rat) Q6P719, (Mouse) Q8R3L0, (Human) Q93086, (Mouse) Q91VE2, (Rat) P51578
Entrez Gene ID: (Rat) 303211, (Mouse) 216829, (Human) 5026, (Mouse) 94045, (Rat) 113995
magnesium ion transmembrane transporter activity
copper ion transmembrane transporter activity
manganese ion transmembrane transporter activity
cobalt ion transmembrane transporter activity
nickel cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
purinergic nucleotide receptor activity
transmembrane signaling receptor activity
extracellular ATP-gated cation channel activity
ion channel activity
ATP binding
GTP binding
drug binding
zinc ion binding
cell surface receptor signaling pathway
neuronal action potential
purinergic nucleotide receptor signaling pathway
regulation of skeletal muscle tissue regeneration
protein homooligomerization
cation transmembrane transport
mitophagy in response to mitochondrial depolarization
transport
signal transduction
nervous system development
blood coagulation
positive regulation of calcium ion transport into cytosol
response to ATP
positive regulation of calcium-mediated signaling
magnesium ion transport
cation transport
skeletal muscle tissue growth
cobalt ion transport
copper ion transport
manganese ion transport
nickel cation transport
copper ion transmembrane transport
nickel cation transmembrane transport
manganese ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support