Invitrogen

PACS2 Polyclonal Antibody

PACS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PACS2 Antibody (PA5-72866) in IHC (P)

Immunofluorescence of PACS2 in mouse brain tissue with PACS2 Polyclonal Antibody (Product # PA5-72866) at 20 µg/mL. Red: PACS2 Blue: DAPI staining

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产品信息

PA5-72866

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

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免疫组化（石蜡） (IHC (P))

5 µg/mL

酶联免疫吸附实验 (ELISA)

Assay-Dependent

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

PACS2 antibody for a 17 amino acid peptide near the center of human PACS2. The immunogen is within amino acids 330 - 380 of PACS2.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2718720

靶标信息

PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Knockdown of circ_0002194 protects against oxidized low-density lipoprotein-induced cell damage via the regulation of the miR-637/PACS2 axis in human vascular endothelial cells.

Interactive cardiovascular and thoracic surgery

Mei R,Wu M,Ren F

PA5-72866 was used in Western Blotting to demonstrate that circ_0002194 facilitated endothelial cell dysfunction in atherosclerosis partly through upregulating PACS2 by targeting miR-637.

Fri Sep 09 00:00:00 UTC 2022

Knockdown of circ_0002194 protects against oxidized low-density lipoprotein-induced cell damage via the regulation of the miR-637/PACS2 axis in human vascular endothelial cells.

Interactive cardiovascular and thoracic surgery

Mei R,Wu M,Ren F

PA5-72866 was used in Western Blotting to demonstrate that circ_0002194 facilitated endothelial cell dysfunction in atherosclerosis partly through upregulating PACS2 by targeting miR-637.