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This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cytoplasmic phosphoprotein PACSIN2; Protein kinase C and casein kinase substrate in neurons 2 protein; Protein kinase C and casein kinase substrate in neurons protein 2; RP3-437M21.1; SdpII; SdpIIsyndapin II; Synaptic dynamin-associated protein II; syndapin 2; Syndapin II; Syndapin-2; Syndapin-II; syndapin2; x-PACSIN2
基因别名: AI197433; PACSIN2; SDPII; XELAEV_18019736mg
UniProt ID: (Human) Q9UNF0, (Rat) Q9QY17, (Mouse) Q9WVE8, (Xenopus) Q9DDA9
Entrez Gene ID: (Human) 11252, (Rat) 124461, (Mouse) 23970, (Xenopus) 398138