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产品信息
H00005058-M02
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
4D1
抗原
PAK1 (NP_002567, 191 a.a. approximately 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: APRPEHTKSV YTRSVIEPLP VTPTRDVATS PISPTENNTT PPDALTRNTE KQKKKPKMSD EEILEKLRSI VSVGDPKKKY TRFEKIGQGA
靶标信息
PAK1 is a serine/threonine kinase that is a target for restenosis, cancer, and immunosuppression treatment. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADRB2; alpha pak; Alpha-PAK; EC 2.7.11.1; kinase PAK1; MGC130000; MGC130001; p21 protein (Cdc42/Rac)-activated kinase 1; p21-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p65-PAK; PAK 1; PAK-1; PAK1B; Serine/threonine-protein kinase PAK 1; STE20 homolog, yeast
基因别名: PAK1; PAKalpha
UniProt ID: (Human) Q13153
Entrez Gene ID: (Human) 5058
MAPK cascade
mitotic cell cycle
response to hypoxia
positive regulation of protein phosphorylation
stimulatory C-type lectin receptor signaling pathway
protein phosphorylation
exocytosis
apoptotic process
axonogenesis
positive regulation of cell proliferation
positive regulation of cell migration
T cell costimulation
actin cytoskeleton reorganization
cellular response to insulin stimulus
positive regulation of peptidyl-serine phosphorylation
positive regulation of intracellular estrogen receptor signaling pathway
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
wound healing
positive regulation of JUN kinase activity
protein autophosphorylation
ephrin receptor signaling pathway
branching morphogenesis of an epithelial tube
neuron projection morphogenesis
T cell receptor signaling pathway
positive regulation of stress fiber assembly
negative regulation of cell proliferation involved in contact inhibition
