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产品信息
PA5-69201
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the N terminal region of human PAR6
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2689381
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
靶标信息
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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生物信息学
蛋白别名: PAR-6; par-6 (partitioning defective 6,) homolog alpha; PAR-6 alpha; par-6 partitioning defective 6 homolog alpha; PAR6C; Partitioning defective 6 homolog alpha; partitioning defective-6 homolog alpha; partitioning-defective protein 6; Tax interaction protein 40; Tax-interacting protein 40; TIP-40
基因别名: 0710008C04Rik; 2610010A15Rik; Par-6; PAR-6A; PAR6; PAR6A; PAR6alpha; PAR6C; PARD6A; TAX40; TIP-40
UniProt ID: (Human) Q9NPB6, (Mouse) Q9Z101
Entrez Gene ID: (Human) 50855, (Mouse) 56513
negative regulation of protein phosphorylation
cell cycle
transforming growth factor beta receptor signaling pathway
viral process
cell-cell junction maintenance
cell division
Wnt signaling pathway, planar cell polarity pathway
regulation of cellular localization
bicellular tight junction assembly
establishment of cell polarity
