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Keep as concentrated solution.
Predicted reactivity: Mouse (89%), Rat (91%), Pig (93%), Chimpanzee (99%), Bovine (92%).
Positive Control: A431, HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PBK (TOPK) is a serine/threonine kinase that is related to the dual specific mitogen-activated protein kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis). Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer/testis antigen 84; CT84; epididymis luminal protein 164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PDZ-binding kinase; serine/threonine protein kinase; Spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase
基因别名: CT84; HEL164; Nori-3; PBK; SPK; TOPK
UniProt ID: (Human) Q96KB5
Entrez Gene ID: (Human) 55872