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产品信息
H00005108-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PCM1 (AAH00453.1, 1 a.a. approximately 530 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MATGGGPFED GMNDQDLPNW SNENVDDRLN NMDWGAQQKK ANRSSEKNKK KFGVESDKRV TNDISPESSP GVGRRRTKTP HTFPHSRYMS QMSVPEQAEL EKLKQRINFS DLDQRSIGSD SQGRATAANN KRQLSENRKP FNFLPMQINT NKSKDASTSP PNRETIGSAQ CKELFASALS NDLLQNCQVS EEDGRGEPAM ESSQIVSRLV QIRDYITKAS SMREDLVEKN ERSANVERLT HLIDHLKEQE KSYMKFLKKI LARENEEEDV RTIDSAVGSG SVAESTSLNI DVQSEASDTT ARDPQQEPME EIENLKKQHD LLKRMLQQQE QLRALQGRQA ALLALQHKAE QAIAVMDDSV VAETAGSLSG VSITSELNEE LNDLIQRFHN QLRDSQPPAV PDNRRQAESL SLTREVSQSR KPSASERLPD EKVELFSKMR VLQEKKQKMD KLLGELHTLR DQHLNNSSSS PQRSVDQRST SAPSASVGLA PVVNGESNSL TSSVPYPTAS LVSQNESENE GHLNPSEKLQ
靶标信息
PCM-1 is required for centrosome assembly and function. This protein is essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. The protein is required to anchor microtubules to the centrosome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hPCM-1; PCM-1; Pericentriolar material 1 protein; pericentriolar material 1, PCM1
基因别名: PCM1; PTC4; RET/PCM-1
UniProt ID: (Human) Q15154
Entrez Gene ID: (Human) 5108
G2/M transition of mitotic cell cycle
neuron migration
interkinetic nuclear migration
cytoplasmic microtubule organization
microtubule anchoring
microtubule anchoring at centrosome
nonmotile primary cilium assembly
intraciliary transport involved in cilium morphogenesis
cilium assembly
negative regulation of neurogenesis
centrosome organization
protein localization to centrosome
positive regulation of intracellular protein transport
neuronal stem cell population maintenance
