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Immunogen sequence: PVYDDGPAGP DAEEAGDETP DVDPELLRYL LGRILAGSAD SE
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 81%.
The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: granin-like neuroendocrine peptide; pro-SAAS; Proprotein convertase 1 inhibitor; Proprotein convertase subtilisin/kexin type 1 inhibitor; ProSAAS
Gene Aliases: BigLEN; PCSK1N; PEN; PROSAAS; SAAS; SCG8; SgVIII
UniProt ID: (Human) Q9UHG2
Entrez Gene ID: (Human) 27344
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