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产品信息
PA5-98039
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Proprotein convertase subtilisin/kexin type 5 protein (201-500AA)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2812653
靶标信息
PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PC5; PC6; prohormone convertase 5; Proprotein convertase 5; Proprotein convertase 6; Proprotein convertase subtilisin/kexin type 5; protease PC6; rPC5; subtilase; Subtilisin/kexin-like protease PC5
基因别名: PC5; PC6; PC6A; PCSK5; SPC6
UniProt ID: (Human) Q92824, (Rat) P41413
Entrez Gene ID: (Human) 5125, (Rat) 116548
kidney development
renin secretion into blood stream
cardiac septum development
signal peptide processing
cell-cell signaling
determination of left/right symmetry
heart development
embryo implantation
anterior/posterior pattern specification
protein processing
peptide hormone processing
viral life cycle
respiratory tube development
nerve growth factor processing
limb morphogenesis
cytokine biosynthetic process
peptide biosynthetic process
embryonic digestive tract development
embryonic skeletal system development
coronary vasculature development
proteolysis
