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PCSK6 Antibody (PA5-68543) in WB
Journal of orthopaedic surgery and research 2023 -
MiR-543 bound to PCSK6 in MH7A cells. A Starbase online database and GSE181614 dataset were used to predict mRNA with miR-543-binding sites. B The effects of miR-543 introduction on MMP3 and PCSK6 expression were determined by qRT-PCR in MH7A cells. C The effect of miR-543 mimics on PCSK6 protein expression was analyzed by western blotting assay. D RIP assay was used to identify the association of miR-543 w... View More
产品信息
PA5-68543
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the N terminal region of human PCSK6
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2692294
产品详细信息
This target displays homology in the following species: Cow: 77%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%
靶标信息
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin-like proprotein convertase 4; Subtilisin/kexin-like protease PACE4
基因别名: PACE4; PCSK6; SPC4
UniProt ID: (Human) P29122
Entrez Gene ID: (Human) 5046
