Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA5-52447
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
007
抗原
Recombinant Rat PCSK9/NARC1 Protein (Gln 31-Gln691)
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: hypercholesterolemia; NARC-1; neural apoptosis regulated convertase 1; Neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; Proprotein convertase 9; proprotein convertase PC9; Proprotein convertase subtilisin/kexin type 9; Subtilisin/kexin-like protease PC9
基因别名: NARC-1; Narc1; PC9; Pcsk9
UniProt ID: (Rat) P59996
Entrez Gene ID: (Rat) 298296
serine-type endopeptidase activity
sodium channel inhibitor activity
low-density lipoprotein particle binding
apolipoprotein binding
very-low-density lipoprotein particle binding
apolipoprotein receptor binding
protein self-association
poly(A) RNA binding
low-density lipoprotein particle receptor binding
very-low-density lipoprotein particle receptor binding
serine protease
kidney development
liver development
negative regulation of receptor recycling
positive regulation of receptor internalization
proteolysis
triglyceride metabolic process
phospholipid metabolic process
apoptotic process
lysosomal transport
cholesterol metabolic process
cellular response to starvation
regulation of receptor activity
negative regulation of low-density lipoprotein particle clearance
protein processing
protein autoprocessing
neurogenesis
neuron differentiation
low-density lipoprotein receptor particle metabolic process
low-density lipoprotein particle receptor catabolic process
regulation of low-density lipoprotein particle receptor catabolic process
cellular response to insulin stimulus
lipoprotein metabolic process
cholesterol homeostasis
regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
