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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
PDC encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. PDC is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 33 kDa phototransducing protein; G beta gamma binding protein; MEKA protein; PHD; Phosducin; phosducin-like orphan protein; Phototransducing protein, 33 kDa (phosducin); Protein MEKA; Rod photoreceptor 1; RPR-1
Gene Aliases: 33DPTP; MEKA; PDC; PHD; PhLOP; PhLP; Rpr-1; Rpr1
UniProt ID: (Human) P20941, (Mouse) Q9QW08, (Rat) P20942
Entrez Gene ID: (Human) 5132, (Mouse) 20028, (Rat) 25343
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