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Positive Control: mouse eye
Predicted Reactivity: Human (100%), Rat (87%), Dog (93%), Cat (94%), Bovine (94%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PDC encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. PDC is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 33 kDa phototransducing protein; G beta gamma binding protein; PHD; Phosducin; phosducin-like orphan protein; Protein MEKA; Rod photoreceptor 1; RPR-1
Gene Aliases: MEKA; PDC; PHD; PhLOP; PhLP; Rpr-1; Rpr1
UniProt ID: (Human) P20941, (Mouse) Q9QW08
Entrez Gene ID: (Human) 5132, (Mouse) 20028
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