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Immunogen sequence: PETKFVKAIV NSCIQHYHDN CLPTIFVYKN GQIEAKFIGI IECGGINLKL EELEWKLAEV G
Antigen sequence identity: Mouse 95%; Rat 92%
Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling. PDCL2 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. PDCL2 has been shown to interact with the chaperonin CCT and is essential for cytoskeletal protein function and cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: phosducin-like 2; Phosducin-like protein 2
Gene Aliases: GCPHLP; PDCL2
UniProt ID: (Human) Q8N4E4
Entrez Gene ID: (Human) 132954
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