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A recommended positive control is rat liver tissue lysate.
PDCL2 antibody is not expected to cross-react with other members of the PDCL protein family.
Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling. PDCL2 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. PDCL2 has been shown to interact with the chaperonin CCT and is essential for cytoskeletal protein function and cell cycle progression.
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Protein Aliases: MgcPhLP; phosducin-like 2; Phosducin-like protein 2; Phosducin-like protein similar 1; protein B
Gene Aliases: 1700010B22Rik; 1700016K07Rik; GCPHLP; Mgcphlp; PDCL2; RGD1559712; Tphlp
UniProt ID: (Human) Q8N4E4, (Mouse) Q78Y63
Entrez Gene ID: (Human) 132954, (Rat) 498352, (Mouse) 79455
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