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产品信息
H00005139-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
5C12
抗原
PDE3A (NP_000912, 533 a.a. approximately 640 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: TPASSLVSKI SAVQFPESAD TTAKQSLGSH RALTYTQSAP DLSPQILTPP VICSSCGRPY SQGNPADEPL ERSGVATRTP SRTDDTAQVT SDYETNNNSD SSDIVQNE
靶标信息
Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cAMP phosphodiesterase, myocardial cGMP-inhibited; cGI-PDE; CGI-PDE A; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A; cGMP-inhibited cAMP phosphodiesterase; Cyclic GMP-inhibited phosphodiesterase A; phosphodiesterase 3A, cGMP-inhibited
基因别名: CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB; PDE3A
UniProt ID: (Human) Q14432
Entrez Gene ID: (Human) 5139
oocyte maturation
cAMP catabolic process
lipid metabolic process
diterpenoid metabolic process
cAMP-mediated signaling
cGMP-mediated signaling
regulation of meiotic nuclear division
response to drug
negative regulation of apoptotic process
negative regulation of vascular permeability
positive regulation of vascular permeability
response to cAMP
positive regulation of oocyte development
cellular response to cGMP
cellular response to transforming growth factor beta stimulus
