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PDE6D Antibody (MA5-47012) in IHC (P)
Immunohistochemistry analysis of PDE6D in paraffin-embedded mouse eye. Green: PDE6D stained by PDE6D monoclonal antibody (Product # MA5-47012) diluted at 1:100. Red: beta Tubulin 3/ Tuj1, a neural marker, stained by beta Tubulin 3/ Tuj1 antibody [GT11710] diluted at 1:500. Blue: Fluoroshield with DAPI. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
MA5-47012
产品规格
种属反应
Dog,
Cat,
Human,
Mouse,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL1359
抗原
Full length human PDE6D Recombinant protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2938084
产品详细信息
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
靶标信息
PrBP/delta, previously known as PDE6/delta, is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system. There are five different subunits consisting of rod and cone specific catalytic subunits: alpha (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family). PRBP/delta has been implicated in the transport and membrane targeting of prenylated proteins (including PDE6) from their site of synthesis in the inner segment to their final destination in the outer segment of rods and cones (Norton et. al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cGMP-phosphodiesterase delta subunit; GMP-PDE delta; PDE6D; pde6D gene for cGMP-phosphodiesterase delta subunit; phosphodiesterase 6D, cGMP-specific, rod, delta; Protein p17; Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
基因别名: AI841218; JBTS22; PDE6D; PDED; PrBP/delta; zgc:92605
UniProt ID: (Dog) Q9XT54, (Human) O43924, (Mouse) O55057
Entrez Gene ID: (Dog) 403781, (Human) 5147, (Rat) 363272, (Mouse) 18582, (Zebrafish) 436981
