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产品信息
PA5-106500
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PDGFRL(Accession Q15198), corresponding to amino acid residues A88-T138.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854169
产品详细信息
Antibody detects endogenous levels of total PDGFRL.
靶标信息
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Platelet-derived growth factor receptor-like protein; platelet-derived growth factor-beta-like tumor suppressor
基因别名: 1110039P19Rik; AV013190; PDGFRL; PDGRL; PRLTS
UniProt ID: (Human) Q15198, (Mouse) Q6PE55, (Rat) Q5RJP7
Entrez Gene ID: (Human) 5157, (Mouse) 68797, (Rat) 290771
