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产品信息
PA5-27989
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 78 and 359 of Human Pyruvate Dehydrogenase E1 beta subunit
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545465
产品详细信息
Recommended positive controls: A549, H1299, HCT116, mouse heart, rat heart.
Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (85%), Xenopus laevis (84%), Pig (94%), Chicken (85%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
PDHB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial) is also named as PHE1B. The enzyme, which is found in mitochondria, is one of the component enzymes of the pyruvate dehydrogenase multienzyme complex (PDH). It catalyzes the first reaction of an oxidative decarboxylation sequence converting pyruvate to acetyl-CoA and CO(2). Defects in PDHB are the cause of pyruvate dehydrogenase E1-beta deficiency (PDHBD).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PDHE1-B; Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; pyruvate dehydrogenase, E1 beta polypeptide
基因别名: 2610103L06Rik; AL024199; C81408; PDHB; PDHBD; PDHE1-B; PHE1B
UniProt ID: (Human) P11177, (Rat) P49432, (Mouse) Q9D051
Entrez Gene ID: (Human) 5162, (Rat) 289950, (Mouse) 68263
glucose metabolic process
acetyl-CoA biosynthetic process from pyruvate
pyruvate metabolic process
tricarboxylic acid cycle
regulation of acetyl-CoA biosynthetic process from pyruvate
glyoxylate metabolic process
mitochondrial acetyl-CoA biosynthetic process from pyruvate
carbohydrate metabolic process
metabolic process
oxidation-reduction process
