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PDIA6 Antibody (MA5-49265) in ICC/IF
Immunocytochemistry analysis of PDIA6 in HEPG2 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in PDIA6 Monoclonal antibody (Product # MA5-49265) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Mouse IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate fo... View More
产品信息
MA5-49265
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
3H5E7
抗原
E.coli-derived human PDIA6 recombinant protein (Position: L20-L440).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3074923
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
靶标信息
P5 is a novel protein that was originally identified in humans. Functionally, P5 has been shown to have peptide binding ability and chaperone activity specific to certain proteins. P5 shares several structural similarities to PDI, an important protein of the ER. The deduced amino acid sequence of P5 shows that it contains the ER retention signal KDEL. P5 also contains two CXXC-like motifs, a motif responsible for oxidoreductase activity. These two CXXC motifs are found on the N- and C-terminus of the protein, one at each end. Studies suggest that the N-terminal CXXC motif is more important than the second for isomerase activity. Contrary to most of the PDI-like proteins, P5 is not stress-inducible.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endoplasmic reticulum protein 5; ER protein 5; protein disulfide isomerase family A, member 6; Protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; Protein disulfide-isomerase A6; thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain-containing protein 7
基因别名: ERP5; P5; PDIA6; TXNDC7
UniProt ID: (Human) Q15084
Entrez Gene ID: (Human) 10130
