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Product Details
PA5-120280
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 72-260 of human PDP1 (NP_060914.2).
Conjugate
Form
Liquid
Concentration
3.41 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2913852
Product Specific Information
Positive test controls include: 293T, U-87MG, DU145, 5637, mouse brain, mouse skeletal muscle, mouse heart, rat skeletal muscle, rat heart. The target is usually found in the following locations: Mitochondrion matrix.
Immunogen sequence: ASTPQKFYLT PPQVNSILKA NEYSFKVPEF DGKNVSSILG FDSNQLPANA PIEDRRSAAT CLQTRGMLLG VFDGHAGCAC SQAVSERLFY YIAVSLLPHE TLLEIENAVE SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESTDID VKEALINAFK RLDNDISLEA QVGDPNSFL
Target Information
PDP1 is a Pyruvate dehydrogenase and helps catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; FLJ32517; FLJ56179; MGC119646; PDP 1; PDPC 1; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; Pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 1; pyruvate dehydrogenase phosphatase isoenzyme 2; pyruvate dehydrogenase phosphatase, catalytic subunit 1
Gene Aliases: Gm1024; PDH; PDP; PDP1; PDPC; PPM2A; PPM2C
UniProt ID: (Human) Q9P0J1, (Rat) O88483, (Mouse) Q3UV70
Entrez Gene ID: (Human) 54704, (Rat) 54705, (Mouse) 381511
magnesium ion binding
protein serine/threonine phosphatase activity
magnesium-dependent protein serine/threonine phosphatase activity
[pyruvate dehydrogenase (lipoamide)] phosphatase activity
calcium ion binding
protein binding
protein complex binding
metal ion binding
catalytic activity
phosphoprotein phosphatase activity
hydrolase activity
protein phosphatase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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