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Product Details
PA5-78679
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PDP 1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 0.1M glycine, 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2736336
Product Specific Information
Positive Control: Mouse testis
Predicted Reactivity: Human (100%), Rat (97%), Xenopus laevis (80%), Chicken (85%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PDP1 is a Pyruvate dehydrogenase and helps catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; FLJ32517; FLJ56179; MGC119646; PDP 1; PDPC 1; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; Pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 2
Gene Aliases: Gm1024; PDH; PDP; PDP1; PDPC; PPM2A; PPM2C
UniProt ID: (Human) Q9P0J1, (Mouse) Q3UV70
Entrez Gene ID: (Human) 54704, (Mouse) 381511
magnesium ion binding
protein serine/threonine phosphatase activity
magnesium-dependent protein serine/threonine phosphatase activity
[pyruvate dehydrogenase (lipoamide)] phosphatase activity
calcium ion binding
protein binding
protein complex binding
catalytic activity
phosphoprotein phosphatase activity
hydrolase activity
metal ion binding
protein phosphatase
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