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产品信息
PA5-58217
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2645352
产品详细信息
Immunogen sequence: MGKPTSADLK LGLATGPVLF ACQQFPEMNA MIMRRFSLPG DVDRARQYVL QSDGVQQTTY LAQQYCHEAI REISKLRPSP ERDALIQLSE IVLT
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
靶标信息
PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: All trans-polyprenyl-diphosphate synthase PDSS1; All-trans-decaprenyl-diphosphate synthase subunit 1; coenzyme Q1 homolog; Decaprenyl pyrophosphate synthase subunit 1; decaprenyl pyrophosphate synthetase subunit 1; Decaprenyl-diphosphate synthase subunit 1; MGC70953; polyprenyl pyrophosphate synthetase; RP13-16H11.3; Solanesyl-diphosphate synthase subunit 1; subunit 1 of decaprenyl diphosphate synthase; subunit 1 of solanesyl diphosphate synthase; TPT 1; trans-prenyltransferase (TPT); Trans-prenyltransferase 1
基因别名: 2610203G20Rik; 2700031G06Rik; COQ1; COQ10D2; DPS; DPS1; hDPS1; mDLP1; mSPS1; PDSS1; SPS; Sps1; TPRT; TPT; TPT 1
UniProt ID: (Human) Q5T2R2, (Mouse) Q33DR2
Entrez Gene ID: (Human) 23590, (Mouse) 56075
