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Product Details
PA5-42383
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human PEMT (aa 152-199).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2576770
Product Specific Information
Peptide sequence: GWAIMHASPT GLLLTVLVAL TYIVALLYEE PFTAEIYRQK ASGSHKRS
Sequence homology: Cow: 93%; Dog: 86%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 82%
Target Information
This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC2483; PE N-methyltransferase; PEAMT; PEMT2; Phosphatidylethanolamine N-methyltransferase; Phospholipid methyltransferase; PLMT
Gene Aliases: PEAMT; PEMPT; PEMT; PEMT2; PHOMETH; PNMT
UniProt ID: (Human) Q9UBM1, (Rat) Q08388
Entrez Gene ID: (Human) 10400, (Rat) 25511
phosphatidyl-N-methylethanolamine N-methyltransferase activity
phosphatidylethanolamine N-methyltransferase activity
phosphatidylethanolamine binding
phosphatidyl-N-dimethylethanolamine N-methyltransferase activity
N-methyltransferase activity
S-adenosylmethionine-dependent methyltransferase activity
methyltransferase
transferase
metabolite interconversion enzyme
lipid metabolic process
glycerophospholipid metabolic process
phosphatidylcholine biosynthetic process
cell proliferation
negative regulation of cell proliferation
phospholipid biosynthetic process
methylation
response to vitamin
response to drug
response to amino acid
response to ethanol
S-adenosylhomocysteine metabolic process
S-adenosylmethionine metabolic process
positive regulation of lipoprotein metabolic process
positive regulation of protein targeting to mitochondrion
phospholipid metabolic process
response to nutrient
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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