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Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional TLE5 complexes to DNA. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Pf1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor; PHF12; PHF12 (HGNC:20816)
基因别名: 2410142K10Rik; F630045O13; KIAA1523; mKIAA1523; PF1; PHF12
UniProt ID: (Human) Q96QT6, (Mouse) Q5SPL2
Entrez Gene ID: (Human) 57649, (Mouse) 268448