Invitrogen

PGC Monoclonal Antibody (4D7D1)

PGC Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PGC Antibody (MA5-29478) in IHC (P)

Immunohistochemical staining of human PGC in human stomach (from 3 donors) with PGC Monoclonal Antibody (4D7D1) (Product # MA5-29478, 1:60, formalin-fixed paraffin embedded sections).

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产品信息

MA5-29478

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

酶联免疫吸附实验 (ELISA)

1:1,000-1:2,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

4D7D1

抗原

Recombinant Human Pepsinogen C/PGC protein (Met1-Ala388)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2785336

产品详细信息

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human Pepsinogen C/PGC.

靶标信息

Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.

仅用于科研。不用于诊断过程。未经明确授权不得转售。