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Immunogen sequence: AAGGIILTAS HCPGGPGGEF GVKFN
This product targets both PGM1 and PGM5. The sequence similarity between the two genes is very high. The antigen sequence corresponds with PGM5; however, the staining pattern of this product correlates better against the PGM1 gene.
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Phosphoglucomutases (PGM; EC 5.4.2.2) catalyze the transfer of phosphate between the 1 and 6 positions of glucose. Isozymes of PGM are monomeric, with molecular masses of about 60 kD, and are encoded by several genes, including PGM1. In most cell types, PGM1 isozymes predominate, representing about 90% of total PGM activity. One exception is red cells, where PGM2 (MIM 172000) is a major isozyme (Putt et al., 1993 [PubMed 8257433]). [supplied by OMIM].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Glucose phosphomutase 1; PGM 1; Phosphoglucomutase-1
基因别名: CDG1T; GSD14; PGM1
UniProt ID: (Human) P36871
Entrez Gene ID: (Human) 5236