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PGRP-L Antibody (PA5-110102) in WB
Western blot analysis of PGRP-L in extracts of Mouse liver. Samples were incubated with PGRP-L Polyclonal antibody (Product # PA5-110102) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-110102
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PGLYRP2 (NP_4431223)
Conjugate
Form
Liquid
Concentration
1.45 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855513
Product Specific Information
Immunogen sequence: LSQYYGAGVA RDPGFRSNFR RQNGAALTSA SILAQQVWGT LVLLQRLEPV HLQLQCMSQE QLAQVAANAT KEFTEAFLGC PAIHPRCRWG AAPYRGRPKL L
Target Information
Peptidoglycan recognition proteins, such as PGRPL, are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: N-acetylmuramoyl-L-alanine amidase; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L; TagL
Gene Aliases: C730002N09Rik; Pglyrp2; Pglyrpl; PGRP-L; Pgrpl; tagL
UniProt ID: (Mouse) Q8VCS0
Entrez Gene ID: (Mouse) 57757
pattern recognition receptor signaling pathway
immune system process
peptidoglycan catabolic process
detection of bacterium
negative regulation of interferon-gamma production
negative regulation of natural killer cell differentiation involved in immune response
growth of symbiont in host
regulation of inflammatory response
defense response to Gram-positive bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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