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PGRP-L Antibody (MA5-24166) in Flow
Flow cytometry of PGRP-L in Mouse liver single‚cell suspension. Samples were incubated in PGRP-L monoclonal antibody (Product # MA5-24166) or isotype control antibody followed by Allophycocyanin-conjugated Anti-Rat IgG F(ab)2 Secondary Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.
Product Details
MA5-24166
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
439728
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse PGRP-L Ser23-Asn530
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606395
Product Specific Information
In Western blots, no cross-reactivity with recombinant mouse (rm) PGRP-S and rmPGRP-1 beta is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Peptidoglycan recognition proteins, such as PGRPL, are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: N-acetylmuramoyl-L-alanine amidase; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L; TagL
Gene Aliases: C730002N09Rik; Pglyrp2; Pglyrpl; PGRP-L; Pgrpl; tagL
UniProt ID: (Mouse) Q8VCS0
Entrez Gene ID: (Mouse) 57757
pattern recognition receptor signaling pathway
immune system process
peptidoglycan catabolic process
detection of bacterium
negative regulation of interferon-gamma production
negative regulation of natural killer cell differentiation involved in immune response
growth of symbiont in host
regulation of inflammatory response
defense response to Gram-positive bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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