Invitrogen

PHF14 Polyclonal Antibody

1个已发表图片

1 篇参考文献

查看其他3个PHF14抗体

抗体检测数据 (1)
已发表图片 (1)

PHF14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PHF14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

PHF14 Antibody (PA5-51406) in IHC (P)

Immunohistochemical analysis of PHF14 in human colon using PHF14 Polyclonal Antibody (Product # PA5-51406) shows strong nuclear positivity in glandular cells.

PHF14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PHF14 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

PHF14 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of PHF14 in human colon using PHF14 Polyclonal Antibody (Product # PA5-51406) shows strong nuclear positivity in glandular cells.

PHF14 Antibody in Immunohistochemistry (IHC) — Fig. 1 PHF14 is overexpressed in glioblastoma multiforme (GBM) and lower PHF14 expression correlates with better outcome in GBM and LGG. a The cellular location of PHF14 confirmed by immunofluorescence (Scale bar = 50 mum). b Representative stainings of PHF14 in normal brain, grade II, grade III and grade IV glioma (Scale bar = 50 mum). c Correlation of the staining intensity of PHF14 with glioma grade. d - f Correlation of PHF14 mRNA expression with increasing WHO glioma grade according to REMBRANDT, TCGA and FRENCH data. g , h The relationship between PHF14 mRNA expression and molecular pathology of glioma. i , j Upregulation of PHF14 is a dismal prognostic factor in LGG by TCGA database. k Upregulation of PHF14 is a dismal prognostic factor in GBM by REMBRANDT database (*P < 0.05; **P = 0.01; ***P < 0.001; ****P < 0.0001)

产品信息

PA5-51406

应用

建议稀释比

已发表文章

免疫组化 (IHC)

-

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

-

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PHF14. Recombinant protein control fragment (Product #RP-93712).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2645482

产品详细信息

Immunogen sequence: AQKEGLLSEA AAEEDIADPF FAYCKQHADR LDRKWKRKNY LALQSYCKMS LQEREKQLSP EAQARINARL QQYRAKAELA RSTRPQAWVP REKLPRPLTS SASAIRKLMR KAELMGISTD IF

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

靶标信息

PHF14 gene ontology annotations related to this gene include metal ion binding.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Silencing expression of PHF14 in glioblastoma promotes apoptosis, mitigates proliferation and invasiveness via Wnt signal pathway.

Cancer cell international

Wu S,Luo C,Li F,Hameed NUF,Jin Q,Zhang J

Published figure using PHF14 polyclonal antibody (Product # PA5-51406) in Immunofluorescence

Mon Apr 11 00:00:00 UTC 2022

生物信息学

蛋白别名: PHD finger protein 14

查看更多收起

基因别名: KIAA0783; PHF14

查看更多收起

UniProt ID: (Human) O94880

查看更多收起

Entrez Gene ID: (Human) 9678

查看更多收起

zinc ion binding DNA-binding transcription factor zinc finger transcription factor gene-specific transcriptional regulator

negative regulation of transcription from RNA polymerase II promoter lung alveolus development negative regulation of platelet-derived growth factor receptor-alpha signaling pathway negative regulation of mesenchymal cell proliferation involved in lung development