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产品信息
H00009063-B01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PIAS2 (NP_775298.1, 1 a.a. approximately 572 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MADFEELRNM VSSFRVSELQ VLLGFAGRNK SGRKHDLLMR ALHLLKSGCS PAVQIKIREL YRRRYPRTLE GLSDLSTIKS SVFSLDGGSS PVEPDLAVAG IHSLPSTSVT PHSPSSPVGS VLLQDTKPTF EMQQPSPPIP PVHPDVQLKN LPFYDVLDVL IKPTSLVQSS IQRFQEKFFI FALTPQQVRE ICISRDFLPG GRRDYTVQVQ LRLCLAETSC PQEDNYPNSL CIKVNGKLFP LPGYAPPPKN GIEQKRPGRP LNITSLVRLS SAVPNQISIS WASEIGKNYS MSVYLVRQLT SAMLLQRLKM KGIRNPDHSR ALIKEKLTAD PDSEIATTSL RVSLMCPLGK MRLTIPCRAV TCTHLQCFDA ALYLQMNEKK PTWICPVCDK KAAYESLILD GLFMEILNDC SDVDEIKFQE DGSWCPMRPK KEAMKVSSQP CTKIESSSVL SKPCSVTVAS EASKKKVDVI DLTIESSSDE EEDPPAKRKC IFMSETQSSP TKGVLMYQPS SVRVPSVTSV DPAAIPPSLT DYSVPFHHTP ISSMSSDLPG EQRRNDINNE LKLGTSSDTV QQ
靶标信息
This gene encodes a protein involved in the regulation of transcription factors involved in MAP kinase signaling. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. Two alternatively spliced transcripts encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein transferase PIAS2; MGC102682; Miz1; Msx-interacting zinc finger protein; Msx-interacting-zinc finger; PIAS-NY protein; PIASxalpha6; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2; RING-type E3 ubiquitin transferase PIAS2; zinc finger, MIZ-type containing 4
基因别名: 6330408K17Rik; AI462206; ARIP3; AU018068; Dib; DIP; MIZ; MIZ1; PIAS2; PIASX; PIASX-ALPHA; PIASX-BETA; PIASxalpha; PIASxb; PIASxbeta; SIZ2; ZMIZ4
UniProt ID: (Human) O75928, (Mouse) Q8C5D8
Entrez Gene ID: (Human) 9063, (Mouse) 17344
DNA binding
transcription coactivator activity
protein binding
transcription factor binding
zinc ion binding
ligase activity
SUMO transferase activity
ubiquitin protein ligase binding
androgen receptor binding
SUMO ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
protein domain specific binding
estrogen receptor binding
glucocorticoid receptor binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein sumoylation
androgen receptor signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of dendrite morphogenesis
regulation of androgen receptor signaling pathway
negative regulation of androgen receptor signaling pathway
