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产品信息
PA5-20952
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An 18 amino acid peptide near the amino terminus of human PIAS2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152449
产品详细信息
A suggested positive control is rat brain tissue lysate.
PA5-20952 can be used with blocking peptide PEP-1066.
靶标信息
This gene encodes a protein involved in the regulation of transcription factors involved in MAP kinase signaling. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. Two alternatively spliced transcripts encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein transferase PIAS2; MGC102682; Miz1; Msx-interacting zinc finger protein; Msx-interacting-zinc finger; Msx-interacting-zinc finger protein; PIAS-NY protein; PIASxalpha6; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2; RING-type E3 ubiquitin transferase PIAS2; zinc finger, MIZ-type containing 4
基因别名: 6330408K17Rik; AI462206; ARIP3; AU018068; Dib; DIP; MIZ; MIZ1; PIAS2; PIASX; PIASX-ALPHA; PIASX-BETA; PIASxalpha; PIASxb; PIASxbeta; SIZ2; ZMIZ4
UniProt ID: (Human) O75928, (Rat) Q6AZ28, (Mouse) Q8C5D8
Entrez Gene ID: (Human) 9063, (Rat) 83422, (Mouse) 17344
DNA binding
transcription coactivator activity
protein binding
transcription factor binding
zinc ion binding
ligase activity
SUMO transferase activity
ubiquitin protein ligase binding
androgen receptor binding
SUMO ligase activity
protein domain specific binding
estrogen receptor binding
glucocorticoid receptor binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
metabolic process
response to organic substance
protein sumoylation
androgen receptor signaling pathway
response to testosterone
negative regulation of sequence-specific DNA binding transcription factor activity
regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of dendrite morphogenesis
regulation of androgen receptor signaling pathway
negative regulation of androgen receptor signaling pathway
