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PIBF1 Antibody (PA5-91916) in IHC (P)
Immunohistochemistry analysis of PIBF1 in paraffin-embedded human rectal cancer. Samples were incubated with PIBF1 Polyclonal antibody (Product # PA5-91916) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-91916
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PIBF1 (Q8WXW3)
偶联物
形式
Liquid
浓度
0.46 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806325
产品详细信息
Positive Samples: Mouse heart; Cellular Location: Cytoplasm, Nucleus, centriolar satellite, centrosome, cytoskeleton, microtubule organizing center
Immunogen sequence: MSRKISKESK KVNISSSLES EDISLETTVP TDDISSSEER EGKVRITRQL IERKELLHNI QLLKIELSQK TMMIDNLKVD YLTKIEELEE KLNDALHQKQ
靶标信息
Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Centrosomal protein of 90 kDa; CEP90; PIBF; progesterone immunomodulatory binding factor 1; progesterone-induced blocking factor 1; Progesterone-induced-blocking factor 1; RP11-505F3.1
基因别名: C13orf24; CEP90; PIBF; PIBF1; RGD1305077
UniProt ID: (Human) Q8WXW3
Entrez Gene ID: (Human) 10464, (Mouse) 52023, (Rat) 306104
biological_process
immune system process
mitotic metaphase plate congression
activation of JAK1 kinase activity
negative regulation of prostaglandin biosynthetic process
negative regulation of interleukin-12 production
positive regulation of interleukin-10 production
negative regulation of natural killer cell activation
nonmotile primary cilium assembly
negative regulation of tyrosine phosphorylation of Stat4 protein
positive regulation of tyrosine phosphorylation of Stat6 protein
protein localization to centrosome
mitotic spindle assembly
