Invitrogen

PIH1D1 Polyclonal Antibody

查看其他13个PIH1D1抗体

抗体检测数据 (1)

PIH1D1 Antibody in Western Blot (WB)

PIH1D1 Antibody in Western Blot (WB)

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PIH1D1 Antibody (PA5-100302) in WB

Western blot analysis of PIH1D1 in HeLa cell lysate (left lane: treated with blocking peptide). Samples were incubated with PIH1D1 polyclonal antibody (Product # PA5-100302).

PIH1D1 Antibody in Western Blot (WB)

Product Image Gallery

PIH1D1 Antibody in Western Blot (WB) — Western blot analysis of PIH1D1 in HeLa cell lysate (left lane: treated with blocking peptide). Samples were incubated with PIH1D1 polyclonal antibody (Product # PA5-100302).

产品信息

PA5-100302

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human PIH1D1(Accession Q9NWS0), corresponding to amino acid residues E84-N134.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2849816

产品详细信息

Antibody detects endogenous levels of total PIH1D1.

靶标信息

Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Nucleolar protein 17 homolog; PIH1 domain-containing protein 1

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基因别名: 1110061L23Rik; 4933413A04Rik; NOP17; PIH1D1; RGD1309809

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UniProt ID: (Human) Q9NWS0, (Mouse) Q9CQJ2, (Rat) Q4V7F5

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Entrez Gene ID: (Human) 55011, (Mouse) 68845, (Rat) 292898

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RNA polymerase I CORE element sequence-specific DNA binding RNA polymerase I upstream control element sequence-specific DNA binding protein binding protein kinase binding histone binding ATPase binding phosphoprotein binding molecular_function

box C/D snoRNP assembly epithelial cell differentiation chromatin remodeling transcription, DNA-templated positive regulation of protein complex assembly snoRNA localization regulation of histone H3-K4 methylation establishment of protein localization to chromatin positive regulation of protein serine/threonine kinase activity positive regulation of histone H4 acetylation negative regulation of histone H3-K9 dimethylation negative regulation of histone H3-K9 trimethylation positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter positive regulation of glucose mediated signaling pathway regulation of TORC2 signaling positive regulation of TORC1 signaling positive regulation of histone H3-K9 acetylation negative regulation of histone H4-K16 acetylation negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway