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产品信息
PA5-28917
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 895 and 1258 of Human p150(PIK3R4)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546393
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (98%), Rat (98%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: phosphatidylinositol 3-kinase-associated p150; Phosphoinositide 3-kinase adaptor protein; Phosphoinositide 3-kinase regulatory subunit 4; phosphoinositide-3-kinase, regulatory subunit 4; phosphoinositide-3-kinase, regulatory subunit 4, p150; PI3-Kinase p150; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; PI3-kinase VPS15
基因别名: 2210010O15Rik; C730038E05Rik; C85833; D9Ertd418e; p150; PIK3R4; VPS15
UniProt ID: (Human) Q99570, (Mouse) Q8VD65
Entrez Gene ID: (Human) 30849, (Mouse) 75669
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase modulator
protein-binding activity modulator
protein phosphorylation
protein targeting to vacuole
phosphatidylinositol biosynthetic process
macroautophagy
pexophagy
regulation of cytokinesis
receptor catabolic process
toll-like receptor 9 signaling pathway
phosphatidylinositol-3-phosphate biosynthetic process
cellular response to glucose starvation
positive regulation of phosphatidylinositol 3-kinase activity
late endosome to vacuole transport
phosphorylation
