Invitrogen

PIM3 Polyclonal Antibody

PIM3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PIM3 Antibody (PA5-13976) in IHC (P)

Immunohistochemistry analysis of PIM3 in formalin-fixed and paraffin-embedded human hepatocarcinoma tissue. Samples were incubated with PIM3 polyclonal antibody (Product # PA5-13976) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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产品信息

PA5-13976

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫组化（石蜡） (IHC (P))

1:10-1:50

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 259-288 amino acids from the C-terminal region of human PIM3

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Ammonium sulfate precipitation, Size-exclusion - Dialysis

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2163931

产品详细信息

This antibody is predicted to react with rat based on sequence homology.

靶标信息

PIM3 serine/threonine kinase or PIM-3 oncogene belongs to a family of protooncogenes. PIM3 is expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines. PIM3 also expressed in human pancreatic cancer cells and phosphorylates BAD to block Bad-mediated apoptosis in human pancreatic cancer cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine.

仅用于科研。不用于诊断过程。未经明确授权不得转售。