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Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Human (99%), Bovine (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. [UniProt]
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 67-11-3 protein; FLJ20565; hepatocellular carcinoma-related putative tumor suppressor; Liver-related putative tumor suppressor; MGC8850; PIN2 interacting protein 1; pin2-interact; PIN2-interacting protein 1; Pin2-interacting protein X1; PIN2/TERF1-interacting telomerase inhibitor 1; Protein 67-11-3; TRF1-interacting protein 1
基因别名: LPTL; LPTS; PINX1
UniProt ID: (Human) Q96BK5
Entrez Gene ID: (Human) 54984