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PINX1 Antibody (PA5-98747) in WB
Western Blot analysis of PINX1 using a PINX1 Polyclonal antibody (Product # PA5-98747) at a concentration of 3.4 µg/mL. Positive WB detected in: Jurkat whole cell lysate, Mouse liver tissue, Mouse kidney tissue. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 38 kDa.
产品信息
PA5-98747
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human PIN2/TERF1-interacting telomerase inhibitor 1 protein (151-299AA)
偶联物
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2813360
靶标信息
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 67-11-3 protein; FLJ20565; hepatocellular carcinoma-related putative tumor suppressor; Liver-related putative tumor suppressor; LPTS1; MGC8850; PIN2 interacting protein 1; pin2-interact; PIN2-interacting protein 1; PIN2-interacting protein X1; PIN2/TERF1-interacting telomerase inhibitor 1; PIN2/TRF1-interacting protein; Protein 67-11-3; TRF1-interacting protein 1
基因别名: 2210403I16Rik; 2610028A01Rik; 67-11-3; AU024023; LPTL; LPTS; LPTS1; PINX1
UniProt ID: (Human) Q96BK5, (Mouse) Q9CZX5
Entrez Gene ID: (Human) 54984, (Mouse) 72400
telomere maintenance via telomerase
mitotic metaphase plate congression
negative regulation of cell proliferation
negative regulation of protein ubiquitination
regulation of protein stability
negative regulation of telomere maintenance via telomerase
regulation of telomerase activity
negative regulation of telomerase activity
protein localization to chromosome, telomeric region
protein localization to nucleolus
negative regulation of telomere maintenance via telomere lengthening
positive regulation of telomeric DNA binding
positive regulation of protein localization to nucleolus
