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Immunogen sequence: TVSYLLEGGS MAHEDFCGHT GKMNPGDLQW MTAGRGILHA EMPCSEEPAH GLQLWVNLRS SEKMVEPQYQ ELKSEEIPKP SKDGVTVAVI SGEALGIKSK VYTRTPTLYL DF
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Pirin; pirin (iron-binding nuclear protein); pirinin; Probable quercetin 2,3-dioxygenase PIR; Probable quercetinase
基因别名: PIR
UniProt ID: (Human) O00625, (Rat) Q5M827
Entrez Gene ID: (Human) 8544, (Rat) 363465